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논문분류	춘계학술대회 초록집
제목	Etiology-Specific Differences in Dialysis Outcomes: Diabetic Chronic Kidney Disease versus Hypertensive Chronic Kidney Disease
저자	Sajjad Ahmed Khan
출판정보	2026; 2026(1):
키워드	Diabetic kidney disease, Hypertensive kidney disease, Dialysis, Outcomes
초록	Objectives: To compare the outcomes of dialysis among diabetic chronic kidney disease (CKD) versus hypertensive chronic kidney disease; in terms of cardiovascular events, electrolyte abnormalities and all cause mortality following dialysis. Methods: Adult patients (≥18 years) with diagnosed cases of CKD dependent dialysis were divided into two groups: diabetic CKD and Hypertensive CKD. Study was conducted in the TriNetX database and propensity matching was done to eliminate potential biases. Risk ratio, cumulative incidence, hazard ratios were estimated and a p < 0.05, was considered statistically significant. Results: After matching, 78,436 patients were included in each cohort. Compared with hypertensive CKD, diabetic CKD was associated with higher risks of acute myocardial infarction (RR 1.12, HR 1.11, p < 0.001), heart failure (RR 1.09, HR 1.11, p < 0.001), cerebral infarction (RR 1.14, HR 1.13, p < 0.001), and atherosclerosis (RR 1.16, HR 1.17, p < 0.001). Infectious risk was also higher in diabetic CKD, with increased sepsis incidence (RR 1.07, HR 1.06, p < 0.001). Electrolyte disturbances were more frequent among diabetic CKD patients, including hyperkalemia (RR 1.08, HR 1.09, p < 0.001), hyponatremia (RR 1.11, HR 1.10, p < 0.001), hypocalcemia (RR 1.04, HR 1.02, p = 0.003), and hypomagnesemia (RR 1.07, HR 1.06, p < 0.001). All-cause mortality was modestly but significantly higher in diabetic CKD (RR 1.06, HR 1.04, p < 0.001). Conclusion: Diabetic CKD patients dependent on dialysis were associated with a higher rate of complications compared to hypertensive CKD patients emphasizing the need for etiology tailored surveillance.
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