| 초록 |
Objectives: To evaluate the validity of a self-dietary assessment nutrition application (www.nutrirodcal.com) in estimating dietary protein intake compared with protein intake derived from 24-hour urinary urea nitrogen in patients with predialysis CKD. Methods: This prospective validation study enrolled adult patients with CKD stages 3–5 who had not received kidney replacement therapy. Participants recorded their daily dietary intake using the Nutrirodcal application. Dietary protein intake (DPI) estimated by the application was compared with normalized protein equivalent of total nitrogen appearance (nPNA), calculated from 24-hour urinary urea nitrogen collections, at weeks 4, 8, and 12. Agreement and correlation between methods were evaluated using intraclass correlation coefficients (ICC) and Pearson’s correlation coefficients. Results: A total of 21 patients (mean age 60 ± 9.9 years; 57% male) were included. Mean nPNA and application-derived DPI were comparable across all time points. The ICC between nPNA and DPI demonstrated moderate agreement at week 4 (ICC = 0.469, p = 0.014), week 8 (ICC = 0.510, p = 0.008), and week 12 (ICC = 0.413, p = 0.028). Pearson’s correlation coefficients showed significant correlations at week 4 (r = 0.485, p = 0.026) and week 8 (r = 0.510, p = 0.018), with a borderline correlation at week 12 (r = 0.414, p = 0.062). Subgroup analyses suggested stronger correlations in patients with CKD stages 3–4 and in those with body mass index > 23 kg/m². Conclusion: The Nutrirodcal self-dietary assessment application demonstrated acceptable validity for estimating dietary protein intake in patients with pre-dialysis CKD when compared with 24-hour urinary urea nitrogen–derived nPNA. This digital tool may serve as a practical adjunct for nutritional monitoring and counseling in routine CKD care. |