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논문분류	춘계학술대회 초록집
제목	Clinical outcomes in Older Kidney Transplant Recipients: A Propensity ScoreMatched Comparison with CKD Patients
저자	Yu Ho Lee
출판정보	2026; 2026(1):
키워드	kidney transplantation, elderly, all-cause mortality, cardiovascular events, end-stage kidney disease
초록	Objectives: Although kidney transplantation is considered the optimal treatment for end-stage kidney disease (ESKD), its risks and benefits in the elderly remain unclear. This study compared clinical outcomes between kidney transplant recipients and propensity score–matched chronic kidney disease (CKD) patients aged ≥65 years. Methods: Older kidney transplant recipients and CKD patients were obtained from the Korean Organ Transplant Registry (KOTRY) and National Health Insurance Service-Senior Cohort Database, respectively. A 1:1 exact propensity score-matching was performed to account for differences in age, sex, estimated glomerular filtration rate, and index year. The primary outcomes were all-cause mortality, cardiovascular events, progression to ESKD, hospitalization for infection, and cancer. Results: After matching, 802 patients were included in each group. Older kidney transplant recipients had similar risks of all-cause mortality (adjusted hazard ratio [HR] = 0.57, 95% confidence interval [CI] = 0.33–1.01) and cardiovascular events (adjusted HR = 1.31, 95% CI = 0.42–4.05) compared with older CKD patients. The risks of progression to ESKD and infection-related hospitalizations were significantly elevated in the transplant group (adjusted HR = 3.51, 95% CI = 1.07–11.5 and adjusted HR = 3.91, 95% CI = 2.66–5.74, respectively). The incidence of cancer was not different between groups. Conclusion: Among individuals aged ≥65 years, kidney transplantation was not associated with increased risks of all-cause mortality, cardiovascular events, or cancer compared with matched CKD population, while conferring higher risks of kidney failure and infection-related hospitalization.
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