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논문분류	춘계학술대회 초록집
제목	Adjustment of Dietary Protein Intake and Chrononutrition as a Kidney Diseases Preventive Strategy
저자	Kinanthi Pratiwi Safitriani
출판정보	2026; 2026(1):
키워드	chrononutrition, protein, kidney disease
초록	Objectives: Chrononutrition has become a new paradigm for health promotion and clinical intervention in recent years. It aligns with the body’s circadian rhythm to prevent and improve metabolic disorder. One of the keys of nutritional care for renal impairment is protein intake management. Therefore, it holds an important lot to be studied whether the adjustment of dietary protein intake with chrononutrition principles can yield favorable clinical outcomes for kidney disease. Methods: The systematic review was obtained from the analysis and synthesis of the recent journals on Pubmed, Science Direct, Scopus, and Google Scholar. Relevant studies were collected up to January 2026 using the following search term : chrononutrition, protein, and kidney disease. Results: Thirty one articles are collected up to January 2026. There are only 3 articles that match the review criteria. Chrononutrition integrates 3 important dimensions: meal timing, frequency, and dietary regularity. Kidney is a central clock-dependent organ and it’s obtained that protein intake in morning time increases muscle mass formation and insulin hormone sensitivity. Irregular food intake and eating frequency evidently cause disruptions in protein and glucose mechanisms through the balance pathways of hunger and satiety signals and disrupt the central circadian pacemaker, which can increase the risk of CKD. As for meal frequency, eating one meal a day is associated with CKD and eating four times or more is associated with the reduced risk of CKD. Taken together, morning timed protein intake, regular meal time and frequency helps in maintaining circadian rhythm and metabolic homeostasis which contribute to prevent renal disease. Conclusion: Chrononutrition adjusted protein diet has a positive effect on kidney’s health and could help as a lifestyle strategy in CKD prevention and intervention programs. Nevertheless, due to the limitations of the related article, it is required for more in depth research about it.
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