| 초록 |
Objectives: To explore the effect of Qi-tonifying and Blood-activating Formula combined with hemodialysis on nutritional status and prognosis in end-stage renal disease (ESRD) patients, and provide clinical evidence for integrated Modern medicine and Herbal medicine in renal replacement therapy. Methods: 70 maintenance hemodialysis ESRD patients (Jan 2023–Jun 2025) were divided into two groups (35 cases each). The control group received routine hemodialysis and nutritional support, and the observation group was additionally given oral Qi-tonifying and Blood-activating Formula for 3 months. Nutritional indicators, inflammatory factors and adverse event incidences were compared. Results: The observation group had significantly higher serum albumin (38.2±4.5g/L), prealbumin (235.6±32.1mg/L) and hemoglobin (112.3±15.4g/L), and lower C-reactive protein (6.2±2.1mg/L) and tumor necrosis factor-α (12.5±3.4pg/mL) than the control group (all P<0.05). Its cardiovascular adverse event (5.3%) and dialysis-related complication (8.0%) incidences were also significantly lower (all P<0.05). Conclusion: Qi-tonifying and Blood-activating Formula combined with hemodialysis effectively improves ESRD patients’ nutritional status, alleviates inflammation, and reduces adverse events, showing good clinical practicability and a new direction for integrated Modern medicine and Herbal medicine in ESRD treatment. |