| 초록 |
Objectives: High sodium intake contributes to albuminuria and structural kidney damage, accelerating chronic kidney disease (CKD) progression. Although sodium intake remains high in many Asian countries, evidence on its impact in Asian CKD populations is limited and heterogeneous. This scoping review mapped existing evidence and identified research gaps. Methods: PubMed, Scopus, and ScienceDirect were searched for English-language studies (January 2020-January 2026) reporting measured sodium intake in CKD with or without dialysis by using validated methods. Case reports, reviews, protocols, animal studies, and conditions-specific studies were excluded. Screening included duplicate removal, tittle/abstract review, and full-text assessment. Results: A total of 450 studies were recorded, 13 studies were included, primarily from Korea, China, Japan, and the United Arab Emirates. Cohort designs predominated. Sodium intake was mainly assessed using 24-hour urinary sodium excretion and standardized food surveys. Higher sodium levels were consistently associated with faster CKD progression, particularly in patients with proteinuria, as well as increased blood pressure and cardiovascular abnormalities. Educational interventions reduced sodium intake, but evidence for long-term clinical benefit remains inconsistent. Notable gaps include limited randomized controlled trials, underrepresentation of Southeast Asia, and the absence of CKD-specific sodium thresholds for Asian populations. Conclusion: Higher sodium intake is associated with CKD progression and cardiovascular risk in Asian populations. Further prospective and randomized studies are needed to inform region specific sodium recommendations. |