대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Era-Dependent Association Between High Peritoneal Transport Status and Technique Failure in Peritoneal Dialysis
저자	Ho-Joong Yoon
출판정보	2026; 2026(1):
키워드	Peritoneal dialysis, Peritoneal equilibration test, Peritoneal transport status, Technique failure, Competing-risk model
초록	Objectives: High peritoneal transport status has traditionally been linked to adverse outcomes in peritoneal dialysis (PD). However, its clinical relevance in contemporary, individualized PD practice remains unclear. We therefore evaluated its association with technique failure across successive treatment eras. Methods: We conducted a retrospective cohort study of 473 incident PD patients between 2000 and 2023. Baseline peritoneal transport status was determined by the 4-hour dialysate-to-plasma creatinine ratio and categorized as high or non-high. Patients were grouped into three treatment eras reflecting major changes in PD practice. The primary outcome was technique failure, with death and transplantation treated as competing events. Fine–Gray models were used to evaluate associations, including interaction terms between transport status and era. Results: Among the study population, 114 patients (24.1%) were classified as high transporters. In the earliest era, high transport status was associated with nearly twofold higher crude technique failure rates compared with non-high status, whereas this difference largely disappeared in the most recent era. In fully adjusted competing-risk models, high transport status was not independently associated with technique failure, whereas later treatment era and higher serum albumin were protective, and older age increased risk. A significant interaction between transport status and era (p = 0.044) demonstrated attenuation of its prognostic impact in contemporary practice. Conclusion: The clinical significance of high peritoneal transport status appears to be era-dependent and has diminished with the evolution of modern PD care. PET-derived transport characteristics function primarily as tools to guide individualized prescription rather than fixed predictors of outcome.
원문(PDF)	PDF 원문보기

목록

위로가기