대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Hemoglobin Decline Across Chronic Kidney Disease Severity Prior To Dialysis Initiation: A Hospital-Based Study From Indonesia
저자	Jenny Khayla Zahirani
출판정보	2026; 2026(1):
키워드	Chronic kidney disease, Hemoglobin, Anemia, Non-dialysis chronic kidney disease, Chronic kidney disease staging
초록	Objectives: Anemia is a frequent and clinically significant complication of chronic kidney disease, with prevalence and severity increasing as kidney function declines. Advanced kidney impairment is associated with reduced erythropoietin production and greater anemia burden. Evaluating hemoglobin decline across chronic kidney disease severity may provide insight into optimal timing for anemia surveillance prior to dialysis initiation. Methods: This cross-sectional study was conducted at Universitas Sebelas Maret Hospital, Indonesia, between January and December 2025. A total of 122 adult patients with chronic kidney disease were identified from electronic medical records. After excluding patients with acute bleeding, erythropoiesis-stimulating agent therapy, recent transfusion, or ongoing dialysis, 73 patients were included. Chronic kidney disease severity was classified according to Kidney Disease: Improving Global Outcomes guidelines. Due to imbalance across individual stages, patients were grouped into early (stage 1–3) and advanced (stage 4–5) disease. Hemoglobin levels were compared using the Mann–Whitney U test. Effect size was calculated using r. Results: Among 73 patients, 13 (17.8%) had early disease and 60 (82.2%) had advanced disease. The mean hemoglobin level was 8.64 ± 2.47 g/dL. Hemoglobin distribution was non-normal (p = 0.011). Advanced disease was associated with significantly lower hemoglobin levels compared with early disease (U = 8.000, Z = −5.510, p < 0.001), with a large effect size (r = 0.65). Conclusion: Advanced chronic kidney disease is strongly associated with marked hemoglobin reduction prior to dialysis initiation. These findings highlight the substantial anemia burden in late-stage disease and support earlier anemia surveillance strategies in clinical practice.
원문(PDF)	PDF 원문보기

목록

위로가기