대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Risk factors for Peptic ulcer disease in patients with chronic kidney disease
저자	Minah Kim*, Soo-Wan Kim1 and Department of Nephrology, Chonnam National University Hospital, Gwangju, Republic of Korea.
출판정보	2016; 2016(1):
키워드	None
초록	Background: Comparison to the general population, patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) are suffering more gastrointestinal symptom. Also, among the most important mortality factors in these patients, gastrointestinal bleeding , especially peptic ulcer bleeding is considered as a critical issue. There have been some studies about the risk factors and mortality in dialysis patients with peptic ulcer bleeding, but there are lack of data of risk factors of peptic ulcer disease in chronic kidney disease. Methods: We retrospectively analyzed the records of 742 patients diagnosed as chronic kidney disease(eGFR <60mL/min) in the Chonnam National University of Hospital. All patients were undergone the upper endoscopy. We analyzed medical records, medication history, endoscopic findings. In this study, we excluded the patients with life-threatening condition, such as peptic ulcer bleeding. Results: 212 patients had peptic ulcer disease (either gastric ulcer or duodenal ulcer). Peptic ulcer disease occurred more frequently in the elderly(Age>70), male gender. Understandably, those with peptic ulcer disease are represented as an advanced CKD stages.(lower glomerular filtration rate, p=0.002). Through the multivariate analysis of risk factors, male gender, lower systolic blood pressure, low albumin levels (albumin <3.5g/dL) were associated with the incidence of peptic ulcer disease. (p<0.001) Conclusion: Low albumin and male gender, low systolic blood pressure are associated with peptic ulcer disease in CKD patients. But further prospective multi-centered study is required. Table: Table 2.Multivariate analysis of risk factors in peptic ulcer disease.
원문(PDF)	PDF 원문보기

목록

위로가기