대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	AKI-Basic, pathogenesis
저자	Robert A. Star
출판정보	2017; 2017(1):
키워드
초록	Despite the high prevalence and burden of acute and chronic kidney diseases, our understanding of appropriate clinical care and underlying disease pathology is far from complete. Nephrology clinical practice guidelines are littered with “weak” recommendations based on “low” or “very low” evidence. No effective therapies currently exist for AKI, and the few drugs approved for CKD do notwork consistently across the CKD population. Relatively few trials occur in nephrology compared to other medical specialties, and many of the interventions tested in recent AKI and CKD trials have had negative results— often sending us back to the drawing board. The presentation will explain how improved kidney outcomes may best be achieved through complementary approaches that include precision medicine, pragmatic trials and population management. Precision medicine approaches to kidney research aim to identify unique disease subgroups and novel drug targets for each group. Pragmatic trials may cost-effectively test identified treatments in large populations and simple sub-populations. Population health management efforts may be designed to ensure the appropriate delivery of treatments to all individuals with each subpopulation. Health information technologies are critical to both pragmatic trials and population health management and can support precision medicine efforts.
원문(PDF)	PDF 원문보기

목록

위로가기