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논문분류	춘계학술대회 초록집
제목	Differential effect of hemoglobin level on patient mortality according to patient age in end stage renal disease patients
저자	Eun Jeong Ko1, Yong Kyun Kim2, Bum Soon Choi1, Byung Soo Kim1, Cheol Whee Park1, Yong-Soo Kim1, Chul Woo Yang1, Byung Ha Chung1
출판정보	2018; 2018(1):
키워드	Hemoglobin target \| Dialysis patient \| Mortality \| Cardiovascular disease
초록	Objectives: In chronic dialysis patients, achieving an adequate hemoglobin (Hb) concentration is very important because lower than 10 g/dL or higher than 12g/dl can be associated with increased patient mortality. However, it hasn’t been confirmed that it can be applied irrespective of patient age. Therefore, the aim of this study is to investigate the impact of Hb level on the clinical outcomes of dialysis patients according to patient age using the Clinical Research Center registry for end-stage renal disease (CRC-ESRD) data. Methods: A total of 3,409 patients form CRC-ESRD were included. They were divided into three group by age, age<40 (n=488), 4060 (n=1,271). We compared the overall mortality, cardiovascular mortality, all-cause and cardiovascular hospitalization according to mean Hb level. Results: In age<40 group, Hb≥12g/dl group showed higher all-cause mortality (adjusted HR 3.894, 95% CI 1.037-14.624; p=0.044) compared to 10≤Hb<12 g/dl group, whereas HR of cardiovascular hospitalization was higher in Hb<10g/dl group (adjusted HR 2.268; 95% CI 1.044-4.926, p=0.039). Meanwhile, in age≥60 group, all-cause and cardiovascular mortality was higher in Hb<10g/dl (adjusted HR 2.098, 95% CI 1.567-2.808, p<0.001 and adjusted HR 2.796, 95% CI 1.669-4.686, p<0.001) compared to 10≤ Hb<12g/dl group, however the difference between 10≤ Hb<12g/dl group and Hb≥12g/dl was not significant. In 40
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